Abstract We developed a non-destructive and rapid whole-mount bone staining method for small fish, Xenopus laevis, and rodent fetuses (RAP-B).RAP-B does not require skin or soft tissue removal.However, RAP-B requires hair removal from hairy animals, such as adult mice and rats.In the present study, we investigated beefeaters triple flavor twists ha
Summary: Background: Early trials of long-term lenalidomide use reported an increased incidence of second primary malignancy (SPM), including acute myeloid leukaemia and myelodysplastic syndrome.Later, meta-analysis suggested the link to be secondary to lenalidomide in combination with melphalan.Methods: Myeloma XI is a large, phase III randomised
Colorectal cancer (CRC), which develops from the gradual evolution of tubular adenomas and serrated polyps in the colon and rectum, has a poor prognosis and a high mortality rate.In addition to genetics, lifestyle, and chronic diseases, intestinal integrity and microbiota (which facilitate digestion, metabolism, and immune regulation) could promote
This study examines listening effort, as indexed by pupil dilation, needed for processing foreign-accented speech that varies in intelligibility.Previous research has shown that the magnitude of pupil dilation is influenced by various factors, crucially the amount of noise added to speech.However, the method has not yet been used to examine foreign
Summary: Target of rapamycin complex 1 (TORC1) is a master regulator that monitors the availability of various amino acids to promote cell growth in Saccharomyces cerevisiae.It is activated via two distinct upstream pathways: the Gtr pathway, adifom q red which corresponds to mammalian Rag, and the Pib2 pathway.This study shows that Ser3 was phosph